Synthesis and antifungal bioactivities of 3-alkylquinazolin- 4-one derivatives.
نویسندگان
چکیده
A simple, efficient, and general method has been developed for the synthesis of various 3-alkylquinazolin-4-one derivatives from quinazolin-4-one treated with alkyl bromides under phase transfer catalysis condition. The structures of the compounds were characterized by elemental analysis, IR, (1)H-NMR and (13)C-NMR spectra. Title compound 6-bromo-3-propylquinazolin-4-one (3h) was found to possess good antifungal activity.
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ورودعنوان ژورنال:
- Molecules
دوره 11 6 شماره
صفحات -
تاریخ انتشار 2006